Acute Promyelocytic Leukemia, microgranular

Author: Wendy Moreland, MD
Category: Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with t(15;17)(q22;q12); PML-RARA
Published Date: 05/08/2012

Acute Promyelocytic Leukemia, microgranular variant, peripheral blood. 67 year old female with mild leukocytosis and anemia. Promyelocytes in peripheral blood have absence of granules and characteristic bilobed nuclear shape. Flow cytometry revealed cells were positive for CD13/CD33/CD117, and cytoplasmic MPO and negative for CD34. FISH positive for t(15;17).