Smudge cells - 1.

Smudge cells - 1.
Author: Peter Maslak
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Low-grade B-cell lymphoma > Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Published Date: 03/01/2010

Peripheral blood smear from a patient with CLL shows lymphocytes as well as "smudge" cells. The lymphocytes in CLL are fragile and can be damaged when making a smear preparation producing this smudged or smeared appearance.