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The cells in the lesion are much larger than the original neuroblastoma cells. In addition the cells have abundant cytoplasm and large vesicular nuclei. Multiple small nucleoli can be seen in some cells while others have large single nucleolus. These cells are morphologically consistent with ganglion cells and suggest differentiation of the neuroblastoma following chemotherapy. (H&E 40x)
Neuroblastoma Ganglion Cell Differentiation Following Chemotherapy - 8.
#00002926
Author: John Lazarchick
Category: Laboratory Hematology > Non-hematopoietic malignancies involving the blood or bone marrow > Metastatic Neuroblastoma
Published Date: 09/23/2011
Category: Laboratory Hematology > Non-hematopoietic malignancies involving the blood or bone marrow > Metastatic Neuroblastoma
Published Date: 09/23/2011
The cells in the lesion are much larger than the original neuroblastoma cells. In addition the cells have abundant cytoplasm and large vesicular nuclei. Multiple small nucleoli can be seen in some cells while others have large single nucleolus. These cells are morphologically consistent with ganglion cells and suggest differentiation of the neuroblastoma following chemotherapy. (H&E 40x)
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