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Hemophagocytosis. This is bone marrow (hematoxylin and eosin stain) from a 49-year-old male with hepatitis C, who presented with fever of unknown origin and multi-organ failure. Bone marrow biopsy revealed hypercellularity with diffuse histiocytic infiltrate and hemophagocytosis. Clusters of lymphocytes in the bone marrow were positive for Epstein-Barr virus (EBV) by in situ hybridization, and peripheral blood was positive for EBV by polymerase chain reaction (PCR). This image shows two macrophages which have phagocytosed numerous erythrocytes.
Hemophagocytosis: Bone Marrow Biopsy of Patient With Hepatitis C and Acute EBV Infection - 1.
#00003224
Author: Jon Fukumoto
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 07/01/2006
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 07/01/2006
Hemophagocytosis. This is bone marrow (hematoxylin and eosin stain) from a 49-year-old male with hepatitis C, who presented with fever of unknown origin and multi-organ failure. Bone marrow biopsy revealed hypercellularity with diffuse histiocytic infiltrate and hemophagocytosis. Clusters of lymphocytes in the bone marrow were positive for Epstein-Barr virus (EBV) by in situ hybridization, and peripheral blood was positive for EBV by polymerase chain reaction (PCR). This image shows two macrophages which have phagocytosed numerous erythrocytes.
This image belongs to set:
Hemophagocytosis: Bone Marrow Biopsy of Patient With Hepatitis C and Acute EBV Infection
Hemophagocytosis: Bone Marrow Biopsy of Patient With Hepatitis C and Acute EBV Infection
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