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A 66-year-old female with a history of pancytopenia for the past 11 years. Her CBC showed a hemoglobin of 8 g/dl with an MCV of 106. a WBC of 4000/ul with PMNs predominant and with 1% metamyelocytes and myelocytes, and a platelet count of 57k/ul. Cytogenetic analysis performed on her marrow aspirate revealed a 46, XX karyotype. Her marrow aspirate is hypercellular with myeloid and erythroid series showing full maturation. Megakaryocytes are present and appear normal in number and morphologically. Large cells containing blue-tinted cytoplasm are noted as single cells and in groups in the upper half of this image.
Marrow Histiocytosis - 1.
#00003363
Author: John Lazarchick
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 07/01/2007
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 07/01/2007
A 66-year-old female with a history of pancytopenia for the past 11 years. Her CBC showed a hemoglobin of 8 g/dl with an MCV of 106. a WBC of 4000/ul with PMNs predominant and with 1% metamyelocytes and myelocytes, and a platelet count of 57k/ul. Cytogenetic analysis performed on her marrow aspirate revealed a 46, XX karyotype. Her marrow aspirate is hypercellular with myeloid and erythroid series showing full maturation. Megakaryocytes are present and appear normal in number and morphologically. Large cells containing blue-tinted cytoplasm are noted as single cells and in groups in the upper half of this image.
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