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Toxic granulation - 1.

Toxic granulation - 1.
#00003674
Author: Peter Maslak
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells > Toxic granulation/Dohle bodies  
Published Date: 10/01/2008

Myelopoiesis with toxic granulation in a bone marrow aspirate. Toxic granules are larger, darker, and more prominent than the normal specific granules seen in differentiated myeloid forms. These changes can be seen in a variety of conditions, including infection and cytokine administration.