Dutcher bodies in myeloma

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Dutcher bodies in myeloma

#00060771

Author: Girish Venkataraman, MD, MBBS
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Plasma Cell Neoplasm > Plasma cell myeloma
Published Date: 06/27/2016

Numerous Dutcher bodies are seen as intranuclear inclusions within anaplastic plasma cells replacing this marrow biopsy in a 74 year old man with relapsed multiple myeloma. These Dutcher represent cytoplasmic immunoglobulins which accumulate imparting this eosinophilic globular appearance on the H&E stain.

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