Plasmacytoma

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COLLECTION

Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
ATLAS

Normal and abnormal blood cells
REFERENCE CASES

Complete cases of common blood disorders (peripheral blood, bone marrow, and diagnostic studies).
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Plasmacytoma

#00061098

Author: Anuradha Bhavsar MD; David Sukhai MD MBA; Kenneth Rosario MD; Eva Gupta MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Plasma Cell Neoplasm
Published Date: 07/20/2017

A 55-year-old male with history of multiple myeloma presented to the hospital with lower right back pain 3 years after chemotherapy. He completed treatment including Velcade, Dexamethasone, and Revlimid before being lost to follow up. Imaging revealed a 6x5cm mass eroding the sacrum and ilium and extended into the epidural space of L2. Biopsy revealed images above:

-H&E: compacted sheets of enlarged plasma cells with profound nuclei
- CD138: +
- Kappa-ISH: +
- Lambda-ISH: -

The images are hallmark of plasmacytoma

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