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Hepatic Large B-cell Lymphoma

Hepatic Large B-cell Lymphoma
#00061499
Author: Gurvinder Dhaliwal; Rupam Sharma; David Sukhai MD MBA; Santosh Kagathur MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Large B-cell lymphomas (not Richter transformation) > Diffuse Large B-cell Lymphoma, not otherwise specified
Published Date: 06/21/2018

A needle core biopsy of a liver mass was conducted in a 63-year-old male. 

Immunohistochemistry results include: High Grade B cell lymphoma, NOS (CD20+, BCL6+, BCL2+, CD10-, CD3-, CD30-, Keratin AE1-3 -, CAM5.2-); KI67 >95% of cells. MUM1+. FISH results: T (14;18) IgH/BCL2 was detected. There was an absence of MYC and BCL2 rearrangements. H&E: poorly differentiated malignant neoplasm with somewhat dis-cohesive cells.

 
     
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