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Thalassemia major case with Howell-jolly bodies and increased NRBC 1
#00062920
Author: Seyed Mohammad Sadegh Pezeshki (M.Sc.); Ali Ashgar Davatgar (M.Sc.)
Category: Red Cell: Disorders of Iron Metabolism and Heme Synthesis > Hemochromatosis > x linked (and other) hereditary sideroblastic anmia > Conditions of ineffective erythropoiesis > β-thalassemia Major and Intermedia
Published Date: 02/12/2020
Category: Red Cell: Disorders of Iron Metabolism and Heme Synthesis > Hemochromatosis > x linked (and other) hereditary sideroblastic anmia > Conditions of ineffective erythropoiesis > β-thalassemia Major and Intermedia
Published Date: 02/12/2020
This is a case of a young female patient with thalassemia major. As you can see in images, there is 3+ anisocytosis (microcytes, normocytes and macrocytes are present) and 3+ poikilocytosis (mostly target cells and schistocytes). There was a slight polychromasia and Howell-jolly bodies (pointed out in pictures) were seen too. Also, white blood cell (WBC) count by auto analyzer was 57.8*103/µL and after evaluation of peripheral blood smear and NRBC correction, corrected WBC was 19.26*103/µL.
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