Thrombotic thrombocytopenic purpura

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Thrombotic thrombocytopenic purpura

#00064963

Author: Ke Xu, MD
Category: Red Cell: Hemolytic Anemia (HA) > Acquired non-immune HAs > Fragmentation Hemolysis > Microangiopathic Hemolytic Anemias > Thrombotic thrombocytopenic purpura
Published Date: 04/01/2024

A 27-year-old female presented with back pain, anemia and thrombocytopenia. Hb 80 g/L, WBC 8x10⁹/L, platelet 5x10⁹/L, creatinine 113 μmol/L. ADAMTS13 level <5 IU/ml. Blood film showed red cell fragmentation, polychromasia and thrombocytopenia. She was diagnosed with immune TTP. She was treated with urgent plasma exchange, methylprednisolone, rituximab and caplacizumab with complete recovery of full blood count and ADAMTS13 level.

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