T-cell prolymphocytic leukemia (T-PLL)

Main Navigation
Account Navigation
Main Content

JavaScript is disabled on your browser

Please enable JavaScript or upgrade to a JavaScript-capable browser to use the ASH Image Bank.

COLLECTION

Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
ATLAS

Normal and abnormal blood cells
REFERENCE CASES

Complete cases of common blood disorders (peripheral blood, bone marrow, and diagnostic studies).
UPLOAD IMAGES

Home / Collection

< Continue browsing

T-cell prolymphocytic leukemia (T-PLL)

#00064966

Author: Davood Bashash; Amir-Mohammad Yousefi; Bahareh Bashiri; Zahra Ghorbani; Hoda Hedayati
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Mature T-cell Leukemias > T cell Prolymphocytic Leukemia
Published Date: 04/02/2024

The patient, a 45-year-old man, was referred due to the sudden onset of symptoms including unexplained weight loss, night sweats, and lymphadenopathies. His complete blood count revealed leukocytosis primarily attributed to lymphocytosis (WBC: 30.78×10⁹/L; ALC: 26.77×10⁹/L). Examination of the peripheral blood smear indicated the presence of small-to-medium-sized cells with irregular, convoluted, and cleaved nuclei. Further analysis through peripheral blood flow cytometry confirmed a diagnosis of T-cell prolymphocytic leukemia (T-PLL), with lymphocytes expressing CD2, CD3, CD5, CD7, CD8, while testing negative for CD1a, CD4, and TdT.

Download Image