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Hematolymphoid neoplasm with PDGFRA rearrangement

Author: Elizabeth L. Courville, MD, 10/02/2015
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement
Published Date: 02/25/2016
     
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The patient was a 30 year old male with eosinophilic pneumonia. The patient also has splenomegaly. FISH analysis identified a CHIC2 deletion (surrogate for FIP1L1-PDGFRA fusion gene).

Final diagnosis: Myeloproliferative neoplasm with eosinophilia associated with FIP1L1-PDGFRA