Author: James W Vardiman
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myelodysplastic Syndromes (MDS) > Myelodysplastic syndrome with isolated del(5q)
Published Date: 12/05/2001
MDS with isolated del(5q) chromosome abnormality. Bone marrow biopsy specimen (H&E stain) and bone marrow aspirate smear (Wright-Giemsa stain). This slide compares the appearance of the hypolobated megakaryocytes in the biopsy section with their appearance in the aspirate smear. In the biopsy section, note the erythroid proliferation. In both figures, note the monolobation of the megakaryocyte nuclei.