Post-polycythemic myelofibrosis, bone marrow core 3

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Post-polycythemic myelofibrosis, bone marrow core 3

#00060157

Author: Elizabeth L. Courville, MD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Polycythemia Vera (PV) > Post-polycythemic myelofibrosis
Published Date: 10/03/2015

H&E stained sections of the trephine core show evidence of marrow fibrosis, with ‘streaming’ of hematopoietic elements and dilated sinuses. There is trilineage hematopoiesis including increased megakaryocytes. Megakaryocytes include atypical forms with hyperchromatic nuclei.

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