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Atypical chronic myeloid leukemia, BCR-ABL1 negative

Author: Elizabeth L. Courville, MD, 10/02/2015
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) > Atypical Chronic Myeloid Leukemia (aCML), BCR-ABL1 negative
Published Date: 02/25/2016
     
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44 year old male.

 

The karyotype was normal. There was no evidence of a BCR/ABL gene fusion by FISH.  By PCR, the sample was negative for BCR-ABL transcripts of the major and minor breakpoint cluster regions.