Chediak Higashi syndrome in accelerated phase

Main Navigation
Account Navigation
Main Content

JavaScript is disabled on your browser

Please enable JavaScript or upgrade to a JavaScript-capable browser to use the ASH Image Bank.

COLLECTION

Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
ATLAS

Normal and abnormal blood cells
REFERENCE CASES

Complete cases of common blood disorders (peripheral blood, bone marrow, and diagnostic studies).
UPLOAD IMAGES

Chediak Higashi syndrome in accelerated phase

#00061666

Author: Reena Das; Rajkumari Banashree Rani
Category: Primary Immunodeficiency (PID) > Other immunodeficiencies > Immunodeficiency with Albinism > Chediak-Higashi Syndrome
Published Date: 07/10/2018

A 2-year-old male presented with fever, jaundice, patchy hypo/hyperpigmentation and hepatosplenomegaly with a clinical diagnosis of Chediak-Higashi syndrome with hemophagocytosis and bicytopenia which led to a bone marrow biopsy.

A. Peripheral blood film showing large abnormal granules in neutrophils and lymphocytes; B. Bone marrow aspirate showing hemophagocytosis in a large histiocyte; C. Bone marrow aspirate showing giant cytoplasmic inclusions in leukocytes and hemophagocytosis; D. Comparison of normal hair and patient hair showing depigmentation and thin hair.

Download Image