l

Normal Lymphoid Tissues: Part 4 - 9.

Normal Lymphoid Tissues: Part 4 - 9.
#00001646
Author: Nancy Lee Harris
Category: Reactive Marrow > Reactive changes
Published Date: 06/20/2002

Adenoid, showing pale staining marginal zone exending toward epithelium of crypt. Specialized lymphoid tissue is found in association with certain epithelia, in particular the naso- and oro-pharynx (Waldeyer's ring: adenoids, tonsils), the gastrointestinal tract (gut-associated lymphoid tissue: Peyer's patches of the distal ileum, mucosal lymphoid aggregates in the colon and rectum), and lung (bronchus-associated lymphoid tissue). Collectively, this is known as mucosa-associated lymphoid tissue (MALT). These tissues tend to have prominent B cell follicles, but also may have discrete T cell zones, similar to the paracortex of lymph nodes. MALT is thought to function in response to intraluminal antigens and the generation of mucosal immunity. Lymphoid cells that respond to antigen in the MALT acquire homing properties that enable them to return to these tissues.