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Different clinical forms of NK/T-cell lymphomas

Different clinical forms of NK/T-cell lymphomas
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Author: Eric Tse and Yok-Lam Kwong
Category: Lymphoma: Mature T and NK cell lymphoproliferations
Published Date: 06/20/2013

Different clinical forms of NK/T-cell lymphomas. (A) Nasal lymphoma showing an initial ulcer (left) that ultimately perforated into the oral cavity, creating a communication between the oral cavity and the nasal cavity. In the past, such a lesion was referred to as “lethal midline granuloma.” (B) Lymphoma initially localized to the calf, presenting as nonhealing ulcers. PET/CT showed occult nasal involvement. This case could be erroneously classified as “nonnasal” lymphoma. (C) Aggressive NK-cell leukemia showing neoplastic cells that were large granular lymphocyte in morphology in the peripheral blood and in the bone marrow (arrow).