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APL - 8.

APL - 8.
#00002606
Author: Peter Maslak
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with t(15;17)(q22;q12); PML-RARA (and variants)
Published Date: 05/24/2004

Diagram of the t(15;17)(q22;q21) rearrangement that characterizes classic APL. This balanced translocation results in the molecular fusion of part of the PML gene at 15q22 with part of the RAR alpha gene from 17q21.

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