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A high power view is shown. Azurophilic granularity can be seen in essentially all of the blasts. Variability in nuclear size and contour is readily noted. Immunophenotypically these cells marked as CD34, CD33, and CD13 positive. The karyotype of the blasts was 49,XY,+8,+9,+11 and +13. These finding were consistent with a diagnosis AML-M1 with precedent myelodysplasia.
CNS Acute Myeloid Leukemia - 5.
#00003066
Author: John Lazarchick
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute myeloid leukemia with myelodysplasia-related changes
Published Date: 04/04/2005
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute myeloid leukemia with myelodysplasia-related changes
Published Date: 04/04/2005
A high power view is shown. Azurophilic granularity can be seen in essentially all of the blasts. Variability in nuclear size and contour is readily noted. Immunophenotypically these cells marked as CD34, CD33, and CD13 positive. The karyotype of the blasts was 49,XY,+8,+9,+11 and +13. These finding were consistent with a diagnosis AML-M1 with precedent myelodysplasia.
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