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Peripheralizing Follicular Lymphoma with Atypical Morphology - 5.

Peripheralizing Follicular Lymphoma with Atypical Morphology - 5.
#00003431
Author: John Lazarchick
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Low-grade B-cell lymphoma > Follicular Lymphoma
Published Date: 07/01/2007

The bone marrow aspirate showed a homogenous infiltrate of small- to medium-sized cells with variable amounts of cytoplasm, regular nuclear borders, and occasional cells with a single large nucleolus. Rare myeloid and erythroid precursors are present. On flow cytometric analysis these cells were κ light chain restricted, CD19, CD20 and CD10 positive. On cytogentic analysis a t(14;18) translocation and an extra chromosome 8 were detected. These findings were consistent with a diagnosis of follicular lymphoma with peripheralization.