An axillary lymph node from a patient with psoriasis is shown. The architectural structure of the node is intact. Irregularly shaped pale staining areas extending from the capsule into deeper areas of the node are typical of dermatopathic lymphadenopathy. The pallor is due to histiocyte proliferation in the paracortical regions of the node. These histiocytes may contain melanin pigment, lipid or hemosiderin.