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AML with histiocytic differentiation is a morphologic variant of acute monocytic leukemia. The cells are large, pleomorphic, and deeply basophilic. There are prominent nucleoli. The cytoplasm contains vacuoles of many sizes. The over-all appearance is reminiscent of tissue histiocytes causing some to propose a separate FAB sub-classification, M5c.
Acute myeloid leukemia with histiocytic differentiation - 1.
#00004043
Author: Abbas Hashim; Nafila Sabeeh;
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > AML not otherwise specified > Acute monoblastic/monocytic leukemia
Published Date: 11/01/2009
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > AML not otherwise specified > Acute monoblastic/monocytic leukemia
Published Date: 11/01/2009
AML with histiocytic differentiation is a morphologic variant of acute monocytic leukemia. The cells are large, pleomorphic, and deeply basophilic. There are prominent nucleoli. The cytoplasm contains vacuoles of many sizes. The over-all appearance is reminiscent of tissue histiocytes causing some to propose a separate FAB sub-classification, M5c.
