Myeloid leukemia associated with Down syndrome 2

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Myeloid leukemia associated with Down syndrome 2

#00060108

Author: Elizabeth L. Courville, MD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Myeloid proliferations related to Down syndrome > Myeloid Leukemia associated with Down Syndrome
Published Date: 09/29/2015

The peripheral blood shows borderline anemia, moderate thrombocytopenia, and circulating blasts (9% blasts by differential count). The blasts have round to slightly irregular nuclear contours, basophilic cytoplasm, and open chromatin. A subset of the blasts have cytoplasmic blebs, and a subset have granules.

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