l

Irregularly contracted cells in oxidative hemolysis

Irregularly contracted cells in oxidative hemolysis
#00060281
Author: Teresa Scordino MD
Category: Morphologic variants of normal cells > Morphologic variants of Red Blood Cells/precursors > Normal Red blood cell morphology with resting lymphocyte for comparison > Poikilocytosis > Oxidative changes  (bite cell)
Published Date: 11/29/2015

Oxidative hemolysis induced by furosemide in a patient with G6PD deficiency.   In oxidative hemolysis, the peripheral smear may show irregularly contracted red blood cells, hemighost or blister cells, and spherocytes.  Irregularly contracted cells lack central pallor, and the hemoglobin appears condensed and irregularly distributed in the red blood cell.