WHIM Syndrome aspirate

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WHIM Syndrome aspirate

#00060454

Author: Katherine Calvo, MD, PhD
Category: Myeloid Disorders > Congenital Neutropenia syndromes > Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome
Published Date: 02/21/2016

30 year old female with longstanding history of warts, hypogammaglobulinememia, infections, and neutropenia. Bone marrow core biopsy shows a hypercellular marrow with

Increased M:E ratio and right shift in granulocytes c/w myelokathexis.

Bone marrow aspirate in the setting of myelokathexis. Neutrophil (center) vacuolated with

nuclear segments connected by thin filamentous chromatin strands

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