Giant Platelet in a Patient with Thrombocytosis

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Giant Platelet in a Patient with Thrombocytosis

#00060761

Author: Akbar Dorgalaleh, Jamal Rashid Panah
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of platelets (cross-reference with specific diagnoses when appropriate > Large and giant platelets
Published Date: 06/03/2016

A patient with chest pain was referred to our center. Complete blood count (CBC) and peripheral blood smear examination revealed a leukocytosis (35000/μl) and a considerable number of hypersegmented neutrophil (>6% with more than 5 lobe). Platelet count of patient also was high (620000/μl). Precise examination of peripheral blood smear showed a number of giant platelets. Platelets were as large as a red blood cell or larger. Giant platelets can be observed in a number of disorders including myelodysplastic syndromes, essential thrombocythemia (ET), Bernard-Soulier syndrome, gray platelet syndrome and May-Hegglin anomaly. Giant platelet, randomly can be observed in normal individuals.

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