Hairy cell leukemia

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Hairy cell leukemia

#00060765

Author: Girish Venkataraman, MD, MBBS
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Splenic lymphomas > Hairy Cell Leukemia
Published Date: 06/27/2016

Circulating hairy cells in a patient with relapse Hairy cell leukemia (HCL).In many cases, especially in older peripheral blood sample, the typical hairy cytomorphology may not be apparent but nuclear characteristics such as monocytoid/dumbbell-shaped nuclei (as seen in the cell on the top right) is also rather characteristic for hairy cells. Flow cytometric demonstration of B-cell markers as well as positivity for CD11c, CD22, CD25, CD103 as well as CD123 allows confirmation of phenotype.

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