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Ewing sarcoma in BMBx with crush artifac

Ewing sarcoma in BMBx with crush artifac
#00060899
Author: Kristian T. Schafernak, M.D.
Category: Laboratory Hematology > Non-hematopoietic malignancies involving the blood or bone marrow > Other Metastatic Malignancy
Published Date: 10/10/2016

Low-power photomicrograph (H&E) of staging bone marrow biopsy for Ewing sarcoma from a teenage boy.  Note the crushed cells at left, which are suspicious for metastatic Ewing sarcoma, as these cells with a high nuclear:cytoplasmic ratio are easily damaged.  CD99 immunostain confirmed involvement by Ewing sarcoma.