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Myeloid sarcoma t(8;21)

Myeloid sarcoma t(8;21)
#00061278
Author: Girish Venkataraman, MD, MBBS
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Myeloid sarcoma
Published Date: 02/24/2018

Acute Myeloid Leukemia with underlying t(8;21) presenting as a relapse in soft tissue. Pax5 (bottom panel) and CD19 were both positive in this case in addition to CD13, CD33, CD56 and CD117. 

Expression of B-lineage antigens is fairly frequent in this AML and does not warrant designation as Mixed phenotype acute leukemia, B-/myeloid.