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T-cell subsets

T-cell subsets
#00061404
Author: Girish Venkataraman, MD, MBBS
Category: Laboratory Hematology > General information about ancillary testing   > Flow cytometry  
Published Date: 04/09/2018

This plot gated on the CD3 positive T cells shows skewed CD4: CD8 ratio with nearly 5 times as many CD8 T cells. The CD4/CD8 negative T-cell population corresponds to an expanded gamma T-cell population which expresses brighter CD3 compared to CD4 CD8 T cells. These cells often express dimmer CD5 but retain CD2 and CD7 compared to TCRalpha/beta+ CD4 and CD8 T-cells.