l

Lymphoglandular Bodies in bone marrow aspirate in a case of B cell lymphoma

Lymphoglandular Bodies in bone marrow aspirate in a case of B cell lymphoma
#00061496
Author: Dr Rupali Parikh; Dr Lakshmi Vaswani; Bhatia Hospital, Mumbai, India
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Low-grade B-cell lymphoma
Published Date: 06/21/2018

Lymphoglandular bodies are cytoplasmic fragments. They appear as pale, agranular and light basophilic with smooth borders. These bodies are commonly observed on fine-needle aspiration cytology smear preparations of lymphoid tissue, often in association with lymphoid malignancies. They have been less frequently reported in bone marrow aspirate smears.

Though the presence of lymphoglandular bodies is not a specific finding theses bodies have been shown to be present in higher numbers in bone marrows involved by B-cell lymphoid malignancies compared with T-cell lymphoid malignancies and myeloid leukemias. They are easily distinguished from platelets by their variable sizes and colour.