Osteosclerosis

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Osteosclerosis

#00061506

Author: Vincent Cracolici, MD; Girish Venkataraman, MD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Myeloproliferative Neoplasms (MPN) > Polycythemia Vera (PV) > Post-polycythemic myelofibrosis
Published Date: 06/28/2018

Photomicrograph of a bone marrow biopsy with osteosclerosis. Osteosclerosis is identified as thickened anastomosing bony trabeculae, often seen in conjunction with a myeloproliferative neoplasm or with metastatic carcinoma in the bone marrow. In this case, the marrow is extensively replaced by a myeloproliferative neoplasm with cords of cells growing in a swirling pattern.

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