#00062303

CD30 immunostain on reactive lymphoid tissue with secondary lymphoid follicles. Note the prominent rimming at the periphery of germinal center with CD30 positive large reactive lymphoid cells compatible with immunoblasts. The perifollicular location is typical for reactive immunoblastic proliferations.

Germinal center B cells mature either into reactive immunoblasts and plasma cells or become memory B cells located outside the mantle zones.