Hairy cell leukemia involving bone marrow, Cyclin D1 positive

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Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
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Hairy cell leukemia involving bone marrow, Cyclin D1 positive

#00062895

Author: Megan Parilla, MD; Girish Venkataraman, MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Splenic lymphomas > Hairy Cell Leukemia
Published Date: 06/29/2020

The bone marrow core biopsy is hypocellular for age (15% cellularity). Clusters of erythroid precursors are increased and show progressive maturation. There are clusters of widely spaced lymphoid cells located in the interstitium. Immunohistochemistry found the lymphoid infiltrate is positive for CD20, and BCL1/Cyclin D1.

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