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Mast cell infiltrate and sinus histiocytosis; H&E; 100X objective.

Mast cell infiltrate and sinus histiocytosis; H&E; 100X objective.
#00062986
Author: Vanessa Kimiko Martin Hoang, DO,MMSc; Le Aye, DO
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Mastocytosis > Systemic Mastocytosis (SM)
Published Date: 04/13/2020

Within the interfollicular areas are scattered small cellular aggregates composed of atypical mast cells admixed with small lymphocytes, plasma cells, and eosinophils.  The sinuses are dilated by histiocytes with foamy cytoplasm and small lymphocytes with spillover into focal aggregates.