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Bone marrow with mast cell infiltrate; H&E; 100X.

Bone marrow with mast cell infiltrate; H&E; 100X.
#00062995
Author: Vanessa Kimiko Martin Hoang, DO,MMSc; Le Aye, DO
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Mastocytosis > Systemic Mastocytosis (SM)
Published Date: 04/13/2020

Low power view of the markedly hypercellular bone marrow trephine biopsy with a diffuse infiltrate of spindled mast cells admixed with thick, pink fibrotic tissue bands, and a small focal area of residual trilineage hematopoiesis.   Note a few scattered dysplastic appearing megakaryocytes with small and hypolobated nuclei.