Therapy-related Myeloid Neoplasm- Bone marrow Aspirate 5

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Therapy-related Myeloid Neoplasm- Bone marrow Aspirate 5

#00063060

Author: Manisha Goel; Girish Venkataraman
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Therapy-related myeloid neoplasms
Published Date: 07/01/2020

Early erythroid precursors like pro-erythroblast and basophilic erythroblast (white arrow) were rather sparse in the smears.

18% blasts with agranular cytoplasm, high N:C ratio and fine chromatin were found on differential count. CD34 immunostain confirmed the blast nature in 10% of these cells. These agranular blasts (black arrow) can be distinguished from early erythroid precursors by lesser basophilia of cytoplasm, finer chromatin and smaller size.

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