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T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia
#00063101
Author: Ke Xu, MD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Precursor Lymphoid Neoplasms > T-lymphoblastic leukemia/lymphoma > Early T-cell precursor lymphoblastic leukemia (provisional)
Published Date: 07/28/2020

Bone marrow smear in T-cell acute lymphoblastic leukemia shows pleomorphic blasts cells and smear cells. Two of the blasts have a hand-mirror conformation (arrows). Flow cytometry shows 32% of blasts. They are CD34+CD7++CD33+CD38+. By intracellular staining, they are TdT+cCD3+.