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Leukemia cutis in acute myeloid leukemia - 2

Leukemia cutis in acute myeloid leukemia - 2
#00063251
Author: Zahraa Akram Alrawi, PhD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016)
Published Date: 10/08/2020

Her peripheral blood counts were as follows: white blood cell [WBC] 24 ×109/L, hemoglobin 10 g/dl, platelet 26×109/L with blast cells forming about 30%. Peripheral smear showed multiple medium to large blasts with scant to moderate amount of cytoplasm.

Bone marrow smears were hypercellular with heavy infiltration by undifferentiated blast cells, heterogeneous in size, moderate to high N/C ratio, visible single nucleoli.

Bone marrow aspirate flow cytometry revealed distinct cell cluster in the blastic region comprising 46% of all gated events with the following phenotype: CD117+, CD7+, CD33+ & HLADR while negative for cMPO, CD19, CD20, CD13, CD14, CD64, confirming the diagnosis of acute myeloid leukemia.