Hairy cell leukemia

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Hairy cell leukemia

#00063258

Author: Ke Xu, MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Splenic lymphomas > Hairy Cell Leukemia
Published Date: 10/08/2020

A 40 year old man presented with cytopenia. Hb131x10^9/L, WBC 3.15x10^9/L, neut 0.95x 10^9/L, plt 77x10^9/L.
Bone marrow aspirate shows increased lymphocytes with cytoplasmic projections. Flow shows 26% lambda restricted CD5- B lymphocytes. They are CD25+CD103+FMC7+CD79b+CD22+. BRAF V600E mutation detected.

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