AML with NPM1 and FLT3 mutations

Main Navigation
Account Navigation
Main Content

JavaScript is disabled on your browser

Please enable JavaScript or upgrade to a JavaScript-capable browser to use the ASH Image Bank.

COLLECTION

Images of peripheral blood and/or bone marrow of blood disorders and normal hematopoiesis.
ATLAS

Normal and abnormal blood cells
REFERENCE CASES

Complete cases of common blood disorders (peripheral blood, bone marrow, and diagnostic studies).
UPLOAD IMAGES

AML with NPM1 and FLT3 mutations

#00063482

Author: Ke Xu, MD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with mutated NPM1
Published Date: 04/01/2021

A 90-year-old patient presented with anemia, thrombocytopenia and high white cell count. Hb 94 g/L, WBC 177 x10^9/L, platelet 33x10^9/L. Blood film showed blasts with cup-shaped nuclear morphology. Flow cytometry identified 90% of blasts. They are CD34-HLADR-CD117+CD33+ cMPO+. Cytogenetic was normal. Molecular diagnostics revealed the NPM1 and FLT3-ITD mutations. Diagnosis of AML with NPM1 and FLT3 mutations was made.

Download Image