T-PLL

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T-PLL

#00063547

Author: Ke Xu, MD
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Mature T-cell Leukemias > T cell Prolymphocytic Leukemia
Published Date: 06/08/2021

The blood film of a patient with T cell prolymphocytic leukemia (T-PLL) showing marked lymphocytosis. Medium sized prolymphocytes with basophilic cytoplasm and single nucleolus, some cells with cytoplasmic blebs. Blood count was Hb 55 g/L, WCC 467.6 x10^9/L (neutrophil 28 x 10^9/L lymphocyte 411 x 10^9/L), Platelet 16 x 10^9/L. Flow cytometry shows 99% of T cells. They are CD3+CD2+CD5+CD7+CD4+CD8-CD10-CD25-CD16-CD56-CD57-.

Lymphocyte count is usually >100x10^9/L in the T-PLL patients and >200x10^9/L in half of the patients.

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