DUTCHER VERSUS RUSSELL BODIES IN PLASMA CELLS

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DUTCHER VERSUS RUSSELL BODIES IN PLASMA CELLS

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Author: Perla Vicari, MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms
Published Date: 06/10/2021

Dutcher and Russell bodies are both intracytoplasmic spherical inclusions of the same origin, i.e., an abnormal accumulation of immunoglobulin. Dutcher bodies (Figures A- arrows) invaginate into or overlie the nucleus (intranuclear pseudo inclusions) whereas Russell (Figures B- arrows) bodies are clearly seen to be within the cytoplasm. They occur in neoplastic plasma or plasmacytoid cells, in multiple myeloma and in other B-cell neoplasms.

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