Target cells

Target cells
Author: Swetha Prabu; Girish Venkataraman
Category: Laboratory Hematology > Basic cell morphology >  Red Blood Cell shape abnormalities > Target cells
Published Date: 06/11/2021

  • Target cells [showed by black arrows] are poikilocyte also called as codocytes ["codo"- bell - shaped as seen in electron microscopy].
  • It is characterised by redistribution of hemoglobin in the periphery and in the centre of the cell separated by a pale region.
  • Redistribution is a result of increased surface area to volume ratio of Red Blood Cells.
  • Target cells is seen in thalassemia, sickle cell disease, liver disease, postsplenectomy, as well as  Hemoglobin C disease.