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Cup-Like Blast

Cup-Like Blast
#00063612
Author: Perla Vicari, MD, PhD
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with mutated NPM1
Published Date: 08/12/2021

Bone marrow aspiration showing myeloid blast with “Cup-like” nuclear invagination in acute myeloid leukemia (arrow). Cup-Like morphology is significantly associated with mutations in FLT3 and NPM1 genes. (May-Grünwald-Giemsa stain)