Sickle Cell Anemia

Sickle Cell Anemia
Author: Jenna Jazayerli; Girish Venkataraman MD
Category: Red Cell: Hemoglobin disorder > Sickle cell anemia and related sickling syndromes > Sickle cell Anemia (HbSS)
Published Date: 06/18/2022

This peripheral blood smear comes from a patient with sickle cell anemia. The blue arrow points out a healthy red blood cell compared to a sickled one identified by the red arrow. The disease causes red blood cells to alter in shape and size, as seen. The yellow arrow labels a neutrophil which helps fight bacteria in the bloodstream. Sickle cell anemia is caused by a point mutation in the beta chain of the globin molecule.