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Prolymphocytic progression of CLL

Prolymphocytic progression of CLL
#00064351
Author: Ke Xu, MD
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Low-grade B-cell lymphoma > Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Published Date: 03/20/2023

The blood film of a patient with prolymphocytic progression of CLL showing large prolymphocytes with prominent nucleoli. CD5 negative kappa restricted B lymphocytes were identified by flow cytometry. Targeted FISH reveals deletion of 17p13 and absence of t(11;14) translocation.