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Apoptotic lymphocyte 1

Apoptotic lymphocyte 1
#00064482
Author: Isil Erdogan Özünal, MD
Category: Laboratory Hematology > Basic cell morphology > Morphologic variants of white blood cells
Published Date: 05/19/2023

Apoptotic lymphocytes on peripheral blood. These are from a patient diagnosed with hairy cell leukemia and treated with 2-chlorodeoxyadenosine (cladribine, 2CDA).  After 2 weeks of the treatment initiation, apoptotic lymphocytes were detected on the blood film. Note the nuclear shrinkage, nuclear condensation, and fragmentation. May-Grünwald Giemsa stain. 
 

 
     
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